Semaglutide injections in Palm Beach Gardens have recently been approved by the FDA for weight loss in individuals with a body mass index (BMI) of 30 or higher. They are also used by those with a BMI of 27 or higher and at least one weight-related health condition, such as high blood pressure or type 2 diabetes. Take a closer look at how this medication works and what clinical trials have shown.
Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist, and it works like a naturally occurring hormone in the body that helps regulate blood sugar levels. GLP-1 also has an effect on appetite and food intake, as it sends signals to the brain that reduce hunger and increase feelings of fullness. By activating the GLP-1 receptor, you decrease food intake and promote weight loss.
When semaglutide is injected into the body, it activates the GLP-1 receptor, which leads to several physiological changes that promote weight loss. First, semaglutide slows down the rate at which the stomach empties, making food stay there for longer periods and leading to increased feelings of fullness and reduced appetite.
Semaglutide also lowers food consumption by reducing cravings and increasing satiety, which leads to a decrease in caloric intake. Third, it reduces glucose production by the liver, helping regulate blood sugar levels and reduce insulin resistance.
Semaglutide also affects the reward center of the brain, which is responsible for the feelings of pleasure and satisfaction associated with eating. By reducing the activation of this reward center, you can reduce cravings for high-calorie foods and the desire to overeat.
The FDA approval of this medication for weight loss was based on the results of four clinical trials, which involved a total of over 4,500 participants. The trials showed that individuals who received semaglutide injections lost significantly more weight than those who received a placebo.
In another trial, participants who received semaglutide lost an average of 15% of their body weight, compared to 2.4% in those who received the placebo.
As with any medication, semaglutide injections may have potential side effects. The most common side effects reported in clinical trials were nausea, diarrhea, vomiting, and constipation. However, these side effects were generally mild and went away over time.
Semaglutide may also have rare but more severe side effects, such as thyroid tumors, acute gallbladder disease, and pancreatitis. Therefore, you need to use the medication under the guidance of a healthcare professional.
Semaglutide injections have been shown to be an effective tool for weight loss in individuals with obesity or excess weight with weight-related health conditions. However, you also need a reduced-calorie diet and increased physical activity for maximum effectiveness.
If you’re considering semaglutide for weight loss, you should discuss the potential benefits and risks with a healthcare provider to determine whether the treatment is an appropriate option. Give us a call for more information!
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